29 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Cardiogenic: Acute MI ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... inopressors #diagnosis #management ... #comparison #table
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Demystified Shock ... Vasopressors #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... Vasopressors #Inotropes #management ... #criticalcare # ... summary #comparison ... #table #pharmacology
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors #Inotropes #criticalcare ... #pharmacology # ... comparison #shock ... #management
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... , Shock where ↑ ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... Thiazide‐like diuretics, MRA ... #Diuretics #Pharmacology ... #Comparison #Table ... CHF #Cardiology #Management
Shock Types and Classification
DISTRIBUTIVE 66%
 • Sepsis/SIRS, anaphylaxis, adrenal insufficiency, liver failure, toxins, spinal/neurogenic
 • Warm
Shock Types and ... CARDIOGENIC 16% • MI ... Cold and Dry #Shock ... #differential #criticalcare
Shock - Differential Diagnosis by Classification

Hypovolemic (Intravascular volume depletion)
 - Hemorrhagic 
   • Trauma
Shock - Differential ... a.k.a. neurogenic shock ... contractility) - Acute MI ... DrEricStrong #Shock ... Classification #Table #CriticalCare
Bedside Classification of Shock

Hypovolemic shock 

- Vomiting, diarrhea, overdiuresis 

- Hemorrhage (GI, peritoneal, RP) 

Distributive shock
Classification of Shock ... Hypovolemic shock ... - Septic shock ... Endocarditis - Post-MI ... #Cardiogenic #Comparison
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
Undifferentiated Shock ... ), LV Failure (MI ... Valves (wide open MR ... ), Neurogenic (SCI ... guyton #curves #criticalcare