28 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... manifestations, hypoxia, CXR ... Leukemia #Hematology #Oncology ... #Diagnosis
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Renal disease - Cr ... Causes of false- ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... and iron release Diagnosis ... composite endpoint of all-cause ... #management #cardiology
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
It is caused by ... actually seen in all ... TreeInBud #Sign #diagnosis ... #clinical #radiology ... #ChestCT #pathophysiology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
Multiple myeloma, CML ... , AML - Large ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... , dyspnea, +/- CXR ... have fever - ACS ... #TLS #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... common • Imaging: CXR ... management #hematology #oncology
Mucoid Degeneration of the ACL
Imaging Findings:
 • T2-hyperintense fluid-signal within the enlarged ACL on both the
Degeneration of the ACL ... within the enlarged ACL ... : • The ACL is ... • ACL ganglion ... #Radiology #diagnosis
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... Causes include: ... ischemic changes CXR ... respiratory distress syndrome ... #cardiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... renal failure Clinical ... at the time of diagnosis ... e.g. incidental CXR