10 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Myeloid Leukemia (CML ... - Hemolytic Anemia ... • Alcohol #gout ... Hyperuricemia #Differential
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The last step in ... #Homeostasis #Gout ... #Pathophysiology ... #Pharmacology # ... Medications #Management
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
ileal conduit - Medications ... Multiple myeloma, CML ... , AML - Large ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... family history - Medications ... changes), high MCV ... anemia (vegan, ... not required in all
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... our patient's out ... to around 500 mL ... Hospitalization #causes #pathophysiology ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... DDX: Rule Out ... Myelogenous Leukemia (CML ... blood count with differential ... progression to AML
Medications Contributing to Dysgeusia

Antimicrobial medicines	Macrolides, fluoroquinolones, ampicillin, metronidazole, tetracycline, trimethoprim-sulfamethoxazole, amphotericin B, terbinafine and other antimycotic
Medications Contributing ... Angiotensin-converting enzyme (ACE ... aripiprazole Gout ... Drugs #Causes #Differential ... #Diagnosis #Pharmacology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Anterior circulation: MCA ... ACA watershed territories ... Reversible course Differential ... Electrolyte abnormality, Medication
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL ... activation and/or medications