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diagnosis causes nephrology potassium renal algorithm high management ammonia continuous crrt disorders diuresis diuretics druginduced encephalopathy endocrinology erythematosus excretion gout
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #differential # ... diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Myeloid Leukemia (CML ... - Hemolytic Anemia ... Sarcoidosis • Hypercalcemia ... Hyperuricemia #Differential
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... Tacrolimus - Amelia ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Clenching of fist ... • NSAIDs • ACE ... Medications 2. ... #differential #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Clenching of fist ... • NSAIDs • ACE ... Medications 2. ... #differential #
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
ileal conduit - Medications ... Multiple myeloma, CML ... , AML - Large ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... family history - Medications ... changes), high MCV ... anemia (vegan, ... not required in all
Continuous Renal Replacement Therapy (CRRT) - Overview Types of CRRT • CVVHD - Continuous Veno-Venous hemodialysis -
electrolytes (essentially hyperkalemia ... refractory) U: uremia ... CRRT Specific Indications ... dialysis dose = 20-25 mL ... 4K, 2K, or 0K (all
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
1.6, low urine Cl ... 0.7, high urine Cl ... with urine Na/Cl ... Other medications ... #diagnosis #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Anterior circulation: MCA ... Reversible course Differential ... Electrolyte abnormality, Medication
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