136 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Antiphospholipid Antibody Syndrome ... Anti-cardiolipin (aCl ... LAC) • Sjogren Syndrome ... Anti-centromere, Scl
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... Primary #Metabolic #Alkalosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... aldosteronism #Metabolic #Alkalosis
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Urinary Chloride • Cl ... Kidney loss of Cl ... - Loss of Cl ... Cystic fibrosis) • Cl ... , Gitelman syndrome
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Chloride Algorithm Cl ... Kidney loss of Cl ... • Loss of Cl- ... Cystic fibrosis Cl ... , Gitelman syndrome
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

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Differential Diagnosis: Rheumatologic ... - MCC systemic ... , SLE, Sjogren syndrome ... Antisynthetase syndrome ... bleomycin, vinca alkaloids
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
- Na-K-2Cl cotransporter ... , K channel, Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... alpha-Intercalated cell Cl
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
acid, Liddle's Syndrome ... R - Cushing's syndrome ... Normotensive: • UCl ... Post-hypercapnia • UCl ... , Gitelman's syndrome
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Likely Metabolic Alkalosis ... Contraction Urine Cl ... Barter, or Gitelman Syndrome ... Elevated #metabolic #alkalosis
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... transformation (CML ... hyperleukocytosis (AML ... Hyperviscosity #Syndrome