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management hematology syndrome causes neurology algorithm hemophagocytic hlh lymphohistiocytosis oncology signs symptoms abscess acromegaly activation arteritis ascorbicacid b12 bandemia behcet
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Pelger-Huet, Macrocytic anemia ... CD23, o CML ... #Diagnosis #Algorithm
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... Clinical Presentation ... Loss of teeth Anemia ... vasculitis Treatment ... #Nutrition #Diagnosis
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
initiation of nutrition ... may cause severe clinical ... hyperparathyroidism Treatment ... #Differential # ... Diagnosis #Pathophysiology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Leukocytosis, anemia ... Lung Abscess Differential ... Abscess #pulmonary #differential
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... : No • Treatment ... #diagnosis #comparison ... #table
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... #management #treatment ... #summary #rheumatology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
intrinsic factor, IF) Clinical ... level (< 200 pg/mL ... Check for IF ab Treatment ... consider other diagnosis ... #management #nutrition
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... likelihood of negative clinical ... #differential # ... #WBC #CBC #hematology ... #pathophysiology
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
- Differential ... Diagnosis Framework ... haptoglobin) 3) Use MCV ... & clinical context ... diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelogenous Leukemia (CML ... Platelet Disorders • Nutritional ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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