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Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... other hormonal causes ... #Workup #Differential ... Diagnosis #algorithm #endocrinology
Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... #Workup #Algorithm ... #differential # ... diagnosis #endocrinology ... #causes #calcium
Causes of Hypercalcemia

#Differential #Hypercalcemia #Diagnosis #Causes #Endocrinology
Causes of Hypercalcemia ... #Differential ... #Hypercalcemia ... #Diagnosis #Causes ... #Endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... #Causes #differential ... calcium #high #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis ... Lymphoma: NHL, CML ... #Differential # ... Diagnosis #Algorithm #causes ... #endocrinology
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... - Differential ... #Differential # ... Diagnosis #Algorithm #Causes ... #endocrinology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Polyneuropathy, Acute ... stroke, Acute spinal ... Hyporeflexia: • Hypercalcemia ... Hyperreflexia: • Hypocalcemia ... #differential #
Hypocalcemia Differential Diagnosis Algorithm
 - Magnesium deficiency
 - Hypoparathyroidism 
 - Hypoalbuminemia (Pseudohypocalcemia)
 - Vitamin D
Hypocalcemia Differential ... deficiency - Acute ... ARUPConsult @ARUPLabs #Hypocalcemia ... Diagnosis #Algorithm #endocrinology ... #differential
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... #workup #differential ... #diagnosis #endocrinology ... elevated #evaluation #workup
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Myeloid Leukemia (CML ... Sarcoidosis • Hypercalcemia ... Diagnosis #Algorithm #endocrinology ... #causes