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diagnosis algorithm dermatology oncology rash rheumatology ana antinuclear causes disorders nuclear patterns petechiae platelet testing activation cancer cytoplasmic framework leukemia
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
with devastating differential ... palpable, the differential ... likely to have thrombocytopenia ... #Diagnosis #Dermatology ... #Nonpalpable #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... hemostasis: - Thrombocytopenia ... #Differential # ... Algorithm #Causes #dermatology ... #physicalexam
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... lymphadenopathy, petechiae ... Labs: anemia, ↑ MCV ... #Leukocytosis #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... History of bleeding (petechiae ... changes), high MCV ... or if a primary hematologic ... Causes #Workup #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... DIC, TTP, HUS - Antibody-mediated ... #Differential # ... Diagnosis #Framework #hematology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
fulminans/DIC, Thrombocytopenia ... (ie petechiae), ... Rash #oncology #differential ... MINTC #Mnemonic #dermatology
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders - Differential ... Environment-mediated - Antibody-mediated ... Platelet #Disorders #Differential ... #Diagnosis #hematology ... #thrombocytopenia
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... #Antinuclear #Antibody ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
mucosal bleeding (Petechial ... leukopenia, anemia, and thrombocytopenia ... 5000 to 10,000 ng/mL ... Diagnosis #Management #Hematology ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Overview: ALL, CML ... involvement CML ... Significant ↓ PLT: Petechiae ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology
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