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Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... #Workup #Algorithm ... #differential # ... diagnosis #endocrinology ... #causes #calcium
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... #Workup #Differential ... Diagnosis #algorithm #endocrinology ... #calcium
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
dihydroxyvitamin D can help differentiate ... between disorders ... Hypoparathyroidism - Calcium-sensing ... Hyperparathyroidism #Diagnosis #Endocrinology ... #Differential
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
algorithm for the workup ... The diagnostic workup ... Urine calcium-creatinine ... sensitivity for correct classification ... #Workup #Differential
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis ... Lymphoma: NHL, CML ... Bony Mets - Calcium ... #Differential # ... Algorithm #causes #endocrinology
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... - Differential ... , Infiltrative disorders ... deficiency • Drugs: Calcium ... #Workup #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Classification ... #Approach #Differential
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... #workup #differential ... #diagnosis #endocrinology ... #calcium #elevated ... #evaluation #workup
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Lymphoproliferative Disorders ... Myeloid Leukemia (CML ... - Hemolytic Anemia ... Sarcoidosis • Hypercalcemia ... Diagnosis #Algorithm #endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... Lithium use • Calcium-sensing ... Vitamin D metabolic disorders ... #Causes #endocrinology ... #diagnosis #differential