8 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Hypernatremia - Differential ... concentrating defect ... diabetes insipidus ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Diagnosis Algorithm ... - Diabetes Insipidus ... #Sodium #nephrology ... #insipidus #DI
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ATPase Nephrogenic diabetes ... insipidus - Vasopressin ... #Kidney #Nephrology ... #Diagnosis #Differential
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... metabolic acidosis • Diabetic ... the excretion of sodium ... and potassium acid ... #nephrology #differential
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Diagnosis Algorithm ... water loss, Serum Sodium ... 300 mmol/kg • Diabetes ... Insipidus Hypodipsia ... Hypernatremia #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... Diagnosis Workup Algorithm ... • Euvolemic: Diabetes ... insipidus (central ... #nephrology #sodium
Diabetes Insipidus - Diagnosis Algorithm
Tests:
 • Osmolality, Urine AND/OR
 • Osmolality, Serum or Plasma AND
 •
Diabetes Insipidus ... - Diagnosis Algorithm ... Plasma AND • Sodium ... #Algorithm #nephrology ... #differential
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
dysfunction - K+ deficits ... insipidus Differential ... Diagnosis: Diabetes ... Insipidus, Impaired ... , Urine Sodium