14 results
diagnosis management rheumatology classification dermatology erythematosus hemophagocytic hlh leukemia lymphohistiocytosis summary syndrome systemic activation antinxp2 antinxp2dm cerebritis chronic cll cns
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Discontinuation of causal ... Manifestations: Malar rash ... Evolution: Chronic disease ... #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... Petechial or purpuric rash ... erythematosus [SLE ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... : SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... Treatment: •
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... such as systemic lupus ... purpura: strong sign ... vasculitis, and SLE
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
classical HL (MCHL ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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