25 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... Diaqnoses: • ... #diagnosis #management ... #treatment #rheumatology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Hematologic ... malignancies Treatment ... Cancer #Oncology #Differential ... #Diagnosis #Classification ... #Nephrology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... Ferritin >3000 ng/mL ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... permeability Diagnosis ... #rheumatology # ... cerebritis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #management #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Criteria for Diagnosis ... Resolution > 15 days Differentials ... : symptomatic treatment ... • Severe disease
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
artery aneurysms Diagnosis ... ) Differential Diagnosis ... Arthritis, AS Treatment ... Behcet #Syndrome #diagnosis ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... in 100 mL boluses ... vaptans (HF/liver disease ... #Diagnosis #Treatment ... #management #nephrology