18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... • Reaction to Medications ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... with Lupus: • Chronic ... activation and/or medications ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... life-threatening • Treatment ... • Evolution: Chronic ... disease Dr. ... Management #Summary #rheumatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... Chronic CPP Crystal ... locations: Wrist, MCP ... Metabolic syndrome • Medications ... Gout #Comparison #rheumatology
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
tablet once daily ... increase to 500 mcg ... recommendations for the treatment ... with chronic bronchitis ... the use of this medication
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... chemotherapy for low-risk disease ... • Indications ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Chronic CPP Crystal ... Resembles RA • Chronic ... locations: Wrist, MCP ... Acute Pseudogout: Treatment ... #Rheumatology #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Inhibitors of Na+K+2Cl ... liver cirrhosis, chronic ... Tolvaptan) • Treatment ... #Pharmacology #Medications ... #Table
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... (Chronic Myeloid ... #Leukemia #Hematology ... #Oncology #Diagnosis