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hematology differential classification myelodysplastic approach diarrhea essential et hematololgy hodgkins kidney lymphoma mcv myelodysplasia nephrology normocytic renal syndrome syndromes thrombocythemia
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... vs Hypocellular MDS ... Expectation • Rx Algorithm ... #Anemia #diagnosis ... #oncology #hematololgy
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... Non-hemolytic: ACD, Aplastic ... Reticulocytosis, MDS ... #MCV #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Deficiency • Aplastic ... #Differential #Diagnosis ... #Algorithm #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Diagnosis #Management ... treatment #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... #Anemia #oncology ... #management
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Corpuscular Volume (MCV ... Algorithm Decreased ... • Marrow Aplasia ... #Algorithm #Causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... • Anemia • Aplastic ... Myelogenous Leukemia (CML ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... classical HL (MCHL ... classification #hematology #oncology ... #management
Post-Transplant Diarrhea - Diagnosis and Management Algorithm Post-transplant diarrhea (≥ 3 loose or liquid stools per day)
and Management ... Malabsorption workup in case ... or switch to EC-MPS ... reduction (5-8 ng/mL ... #Management #Algorithm
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... PV, MDS, CML) Treatment ... transformation into MDS ... • Treatment algorithms ... #management #hematology
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