22 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-histone - Drug-induced ... Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... diseases #diagnosis #table ... #rheumatology #
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels ... #lupus #management
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Arthritis • SLE ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Vascular Resistance, Main ... Uses, Peripheral ... #Pharmacology # ... Effect #Management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... Discontinuation of causal ... #comparison #table ... #rheumatology # ... diagnosis #management
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
- Parasites Drugs ... - DRESS - AIN ... Primary: - CML ... Hypereosinophilic Syndrome ... #hematology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Diagnosis and Management ... disease (rare), and drugs ... , Muscle/joint pain ... hypophysitis, Sheehan's syndrome ... Give 250 mcg of
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-histone (in drug-induced ... SLE) • Systemic ... scleroderma) - Anti-Scl ... • Sjögren syndrome ... antibodies #diagnosis #rheumatology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... A dissociative drug ... No pharmacologic ... (Haldol) - No pharmacologic ... CriticalCare #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... erythematosus [SLE ... ) • Sepsis • Drug-induced ... #Diagnosis #Management ... #Hematology #Rheumatology