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diagnosis management erythematosus hematology lupus systemic clinical oncology physicalexam activation alien anisocoria behcet cerebritis chronic cll cns differential disease horners
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
sclerosis, RA, SLE ... , Sjogren syndrome ... Antisynthetase syndrome ... Carpal tunnel syndrome ... #Syndrome #Differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... 35% • Raynaud phenomenon ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Erythematosus #SLE ... #CNS #neurology ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... hyperimmunoglobulin D syndrome
Horner's Syndrome on Physical Exam A 75yoF was referred in for facial swelling and eyelid changes 1
Horner's Syndrome ... diagnosis of Horner's syndrome ... or induced by treatment ... anterior_seg_rocks #Horners #Syndrome ... #physicalexam #neurology
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 Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... Macrophage #Activation #Syndrome ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... Pinpoint-sized red spots ... ) • Felty Syndrome ... Myelodysplastic Syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren syndrome ... Non-autoimmune rheumatologic ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Paraneoplastic phenomenon ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... • Uhthoff’s phenomena ... Multiple Sclerosis Treatment ... taper 3-7 days - Short ... #treatment #MS
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