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management differential rheumatology oncology abg acid acidbase activation antibiotics apml base bloodgas calcium cancer causes cppd deposition differentiation disease disorders
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... Procalcitonin <0.5 ng/mL ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
cirrhosis, nephrotic syndrome ... Stress, Nausea, Pulmonary ... , CNS Disease, Meds ... #Algorithm #diagnosis ... #nephrology #sodium
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Muscle swelling - Fever ... urine output: 200 ml ... #Differential #Diagnosis ... #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Anterior circulation: MCA ... epilepticus Treatment ... underlying cause • Treatment ... Seizures: Treat with AEDs ... #neurology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Diagnosis of ... Inhibitors of Na+K+2Cl ... Torsemide) • Acute pulmonary ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
: - Fever + ANC ... ): - Hematologic ... fluids (200–300 mL ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
(AG) = {Na - (Cl ... D-lactate (short bowel syndrome ... Anxiety, pain, fever ... Classically” noted with pulmonary ... #Summary #Nephrology
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