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management rheumatology risk stratification differential febrile hemophagocytic hlh infant lp lymphohistiocytosis oncology pediatrics stepbystep abscess adultonset brain causes classification clinical
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... Procalcitonin <0.5 ng/mL ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #LP #Antibiotics
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
: • 80% have fever ... Intervention: - Fevers ... treatment until ... foreign body, cancer ... Lung #Abscess #pulmonary
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... hemopathies, solid cancers ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... rapidly, and empiric antibiotic ... #hematology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
treatment. http ... 92.0% and 46.9% #Diagnosis ... Management #Pediatrics #Peds ... #LP #Antibiotics ... Stratification #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... B-LNH), solid cancers ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
500 → may stop antibiotics ... syndrome): - Hematologic ... fluids (200–300 mL ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... classical HL (MCHL ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... murmur 3/6) - Pulmonary ... event, follow ACC algorithm ... one post op Cardiology ... stratification #diagnosis
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
night sweats, fever ... Cerebral > Splenic, Pulmonary ... hematuria, + RF Treatment ... • IV antibiotics ... #cardiology #infectiousdiseases
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