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diagnosis management nephrology causes syndrome algorithm cancer classification oncology aki chronic disorders emergencies encephalopathy gitelman injury kidney leukostasis lymphomas lymphoproliferative
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... - Differential ... glycosides • High acute ... blockers - MCW ... #HyperKalemia
Algorithm for Management of Acute and Chronic Hyperkalemia Acute Hyperkalemia: - IV calcium (10 mL of 10%)
and Chronic Hyperkalemia ... Acute Hyperkalemia ... binders Chronic Hyperkalemia ... optimization) #Hyperkalemia ... #Chronic #treatment
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Emergencies - Differential ... Diagnosis Framework HEMATOLOGIC ... of breath • Neurologic ... Hyperphosphatemia • Hyperkalemia ... Hyperuricemia • Acute
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... • LDH ↑ • Hyperkalemia ... urine output: 200 ml ... Dialysis for severe hyperkalemia ... #nephrology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... Hypomagnesemia, Acute ... or induced) #Hypokalemia ... #Causes #differential
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... Cancer Related • Hypercalcemia ... change disease • Hematologic ... malignancies Treatment ... Cancer #Oncology #Differential
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - ACS, AKI, acute ... Lysis Syndrome: • Pathophysiology ... hydration - Hyperkalemia ... diagnosis #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Responsive to Treatment ... Treated Like Acute ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... ratio 0.5%) Differential ... #Hypokalemia
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Reversible course Differential ... syndrome, ADEM, Acute
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