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diagnosis rheumatology syndrome hemeonc hemophagocytic hlh leukemia lymphohistiocytosis chronic classification cll cutaneous differential hodgkins lupus lymphocytic lymphoma myelodysplastic reactions table
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... dermatomyositis, SLE ... differential #diagnosis #dermatology ... #oncology #clinical ... #skin
Symptoms Distinguishing Groups of Cutaneous Drug Reactions IgE-mediated reactions: • Onset minutes to hours into treatment course
to hours into treatment ... Raised off of the skin ... Blistering and/or skin ... Drug #Reactions #dermatology ... #clinical #comparison
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
arterial thrombosis, skin ... complex → plt activation ... Diagnosis: • Clinical ... Confirmatory test ↑Se ... #Treatment #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... sequestration and activation ... : 33% • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... Autoimmune diseases • Clinical ... Malignancies (eg CML ... #oncology #diagnosis ... #differential #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #comparison #table ... #rheumatology # ... diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... Ferritin >500 ng/mL ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... Syndrome #diagnosis #management
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