18 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Imaging: CXR- pulmonary ... #management #hematology ... #oncology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... transformation (CML ... hyperleukocytosis (AML ... #Management
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... and AML) and solid ... malignancies Treatments ... #TLS #oncology ... #management #UricAcid
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Antiphospholipid antibodies (aPL ... Anticardiolipin antibodies (aCL ... to be present Treatment ... APS #diagnosis #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... fluids (200–300 mL ... : - Seen with AML ... (~20 %) and APL ... renal failure, pulmonary
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... Mg, preferably Cl ... #Management #Treatment ... #nephrology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... Myelogenous Leukemia (CML ... factor (GCSF) treatments ... progression to AML ... diagnosis #hematology #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management ... #neurology
Man in the Barrel Syndrome on Physical Exam
Bilateral brachial paresis, mainly proximal, with preserved motor function
in the Barrel Syndrome ... Results from ACA-MCA ... #Man #Barrel #Syndrome ... PhysicalExam #clinical #video ... #neurology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Inhibitors of Na+K+2Cl ... Torsemide) • Acute pulmonary ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology