9 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • Infectious ... Complications: MAS ... Disease #diagnosis #management ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
ECG is vital while ... #diagnosis #differential ... #algorithm #management ... #cardiology #treatment ... heartfailure #chf #criticalcare
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Prednisone 5mg/kg ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Management during ... Management during ... months before 1° prevention ... #cardiology #treatment
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... vasculitis vs infection ... of the steroid treatment ... Treatment of GCA ... Symptoms #Diagnosis #Management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
disease flares: • Prevention ... of infections) ... • IVIg 2 g/kg/month ... syndrome #diagnosis #management ... #rheumatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
PV, MDS, CML) Treatment ... of symptoms and prevention ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Triggers: ▪ Infections ... (often termed MAS-HLH ... underlying trigger: Infections ... #Hematology #HemeOnc