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management monoclonal differential gammopathy disease multiple multiplemyeloma oncology ophthalmology sclerosis syndrome treatment agglutinin anemia bee behcet biopsy complications criteria followup
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS) Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... ) Mayo Clinic Risk ... monoclonal #gammopathy #MGUS ... #diagnosis #management ... #hematology #multiplemyeloma
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Neurologic-Centered ... Renal-centered (ie "MGRS ... #Significance #MGUS ... #hematology #oncology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... , low-risk MGUS ... whom there are no clinical ... #diagnosis #management ... #hematology #multiplemyeloma
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • MGCS • MGRS ... Dermato-neuro syndrome) MGRS ... anemia due to cold ... Paraproteinemias #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... symptoms - most ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis (MS ... nearly 3:1 • MS ... resonance imaging [MRI ... criteria for MS ... #treatment #MS
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... swollen, while in MS ... Predictive of MS ... Multiple sclerosis (MS ... #management #neurology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis ... #hematology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... caucasian • Symptoms ... R-G or B-Y • MRI ... - Typical MS-like ... Management #treatment #rheumatology
McDonald Criteria for Diagnosis of Multiple Sclerosis • 2 or more attacks, 2 or more lesions
McDonald Criteria for Diagnosis ... in the spinal cord ... McDonald #Criteria #Diagnosis ... Multiple #Sclerosis #MS ... #neurology
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