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management differential gammopathy monoclonal neurology oncology classification radiology significance agglutinin algorithm amyotrophic anemia arthritis cold complications dermatology disease disorders fungal
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Features: POEMS, AL ... Renal-centered (ie "MGRS ... #Significance #MGUS ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... #Significance #hematology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... circumscribed sclerotic ... - **MSK rads ... #diagnosis #msk ... #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
syndromes such as ... Diagnosis - Based ... resonance imaging [MRI ... patients with clinically ... stimulation Clinical
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Classic - Nodular Sclerosis ... pattern of spread, B symptoms ... not as common ... Classification #pathophysiology ... #Hematology #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... Disorders Such As ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... Pathophysiology ... cellular function Clinical ... fasciculations Common Symptoms ... MRI: Brain, cervical
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... suggestive of multiple sclerosis ... : - Multiple sclerosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Hyperostosis: Sclerotic ... : • A clinical ... - MRI: inflammation ... SAPHO #Syndrome #Rheumatology
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