9 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... Renal-centered (ie "MGRS ... Ig deposition disease ... #MGUS #Differential
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... • Monoclonal gammopathy ... significance (MGRS ... malignancies Treatment ... #Differential #Diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... antibody - Early treatment ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Seronegative Reactive Syndrome ... - Acute rheumatic ... #differential #diagnosis ... #msk #physicalexam
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Diagnosis: • hemolytic ... IgM monoclonal gammopathy ... significance (MGUS
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Include: • MGUS ... changes (POEMS syndrome ... Viral infections (acute ... inflammation (acute ... #differential #diagnosis
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... Albuminuria, nephrotic syndrome ... , or acute nephritis ... ulcerated • MSK ... Syphilis #stages #diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... patients with clinically ... stimulation Clinical ... symptoms) • Acute
Iliotibial Band Friction Syndrome - MSK Radiology
Imaging Findings:
 • The iliotibial band (ITB) is thickened with
Band Friction Syndrome ... - MSK Radiology ... • Treatment: Conservative ... Findings of chronic disease ... #msk #clinical