35 results
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Monoclonal Gammopathy ... UPEP / IFE #Monoclonal ... Protein #Diagnosis #MGRS ... #MGUS #SPEP #IFE
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... Renal-centered (ie "MGRS ... #Gammopathy #Clinical ... #Significance #MGUS
MGRS - Monoclonal Gammopathy of Renal Significance 

#MGRS #Monoclonal #Gammopathy #Renal #Significance #Diagnosis #Pathology
MGRS - Monoclonal ... Significance #MGRS ... #Monoclonal #Gammopathy
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
for follow-up of monoclonal ... significance (MGUS ... ) Mayo Clinic Risk ... #monoclonal #gammopathy ... #MGUS #Followup
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... whom there are no clinical ... #MGUS #Biopsy #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... • MM • WM • MGUS ... • MGCSMGRS ... Dermato-neuro syndrome) MGRS ... WAIHA • CAD • PCH
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... Light-Chain MGUS ... not defined #MGUS
Amyloidosis Diagnosis
1) Patient presentation
 • Cardiac-specific signs of amyloidosis: Diastolic heart failure, Heart failure with preserved
and diarrhea, Monoclonal ... significance (MGUS ... neuropathy, atypical MGUS ... noncardiac signs: monoclonal ... immunofixation: Presence of monoclonal
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... malignancy (CLL) - Monoclonal ... Viral Infection Clinical ... Such As: • IgM monoclonal ... significance (MGUS
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... if this is is monoclonal ... Other causes of a monoclonal ... MultipleMyeloma #Monoclonal ... #Gammopathies #MGUS