2465 results
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... Proteinuria >150mg/d protein ... Myeloma • MGUS ... Diabetes • Protein ... Proteinuria #Nephrology #Differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Feature A Monoclonal Protein ... • MM • WM • MGUS ... • MGCSMGRS ... Dermato-neuro syndrome) MGRS ... Hematology #Monoclonal #Differential
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Gammopathy #Testing #Protein ... #Diagnosis #MGRS ... #MGUS #SPEP #IFE
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Elevated Globulin - Protein ... Gap (Total Protein ... • (Total protein ... Gammopathy Include: • MGUS ... Gap #ProteinGap #differential
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... (IgG type, M- protein ... 8) light-chain MGUS
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... ) - Differential ... Renal-centered (ie "MGRS ... #Significance #MGUS ... #Differential #
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... IgM MGUS: • Serum ... IgM monoclonal protein ... Serum monoclonal protein ... Urinary monoclonal protein
Subtypes of Serum Proteins

Pre-albumin (Transthyretin)
Albumin
Globulins
 • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Subtypes of Serum Proteins ... Retinol-binding protein ... Ceruloplasmin, Protein ... SatyaPatelMD #Serum #Proteins
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... monoclonal #gammopathy #MGUS
Coagulation Protein Tests (PT and PTT)

#Coagulation #Tests #PTT #algorithm #differential #pathophysiology
Coagulation Protein ... PTT #algorithm #differential