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hyperkalemia pharmacology medications nephrology causes high agitation algorithm binder channelblockers criticalcare delirium druginduced drugs elderly geriatrics hypomagnesemia hypomg icu kbinder
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... Decreased renal potassium ... Increased potassium ... #Hyperkalemia #Diagnosis ... #differential
Potassium Channel Blockers - Medications 1. Cardiovascular Drugs 2. Psychiatric drugs 3. Other drugs 4. Synthetic opioids: Levomethadyl 5. Opium
Potassium Channel ... Other drugs 4. ... Organophosphates #Potassium ... #Medications #Differential ... #Diagnosis #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Cyclosporine) • Increased ... #hyperkalemia #differential ... #pharmacology # ... potassium #medications
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
g once daily Increase ... from other oral drugs ... this from other drugs ... after) to avoid interactions ... #Hyperkalemia #Pharmacology
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
osmotic diuresis - Potassium ... renal disease Drugs ... Hypomagnesemia #Causes #diagnosis ... #differential # ... #pharmacology #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... reactions Common Drugs ... hypoperfusion Increased ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... reactions Common Drugs ... hypoperfusion Increased ... #potassium #high
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
Hydromorphone (Dilaudid) - Increased ... A dissociative drug ... metabolism (med interactions ... No pharmacologic ... #CriticalCare #diagnosis
Nephrolithiasis: Medications Associated with Renal Stones • Hypercalciuria: Furosemide, Topiramate, Vitamin D/Calcium, Glucocorticoids • Precipitation of
Precipitation of drug ... , Vitamin C • Increased ... Renal #Stones #pharmacology ... #differential # ... diagnosis #nephrology
Differential Diagnosis: New-Onset Seizure in the Elderly STRUCTURAL: • Stroke/TIA, Subdural hematoma, mass • Traumatic Brain Injury
Differential Diagnosis ... withdrawal • Drug ... interactions ... fivefold to tenfold increased ... #Differential #Diagnosis
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