21 results
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Antiplatelet Drugs ... #Medications #Pharmacology ... #Pathophysiology ... #Drugs #Agents
Delirium in the ICU

Defining delirium
Types of delirium
Consequences of delirium
Reversible causes of delirium
Drug-induced delirium
Non-pharmacologic management of delirium
Pharmacologic
ICU Defining ... Drug-induced delirium ... Pharmacologic ... #Delirium #pharmacology ... #criticalcare #diagnosis
Checklist for Evaluation of New-Onset Delirium in the ICU

Initial assessment 
 - 
Vital signs, neuro exam
in the ICU Initial ... Review recent events ... - Relevant drug ... Evaluation #Workup #MICU ... #CriticalCare #Diagnosis
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Antipsychotic Drugs ... Antiparkinsonian agents ... are diagnostic ... dose or change drug ... #SideEffects #pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
A dissociative drug ... non-OTC prolonging agent ... No pharmacologic ... (Haldol) - No pharmacologic ... #diagnosis #management
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework

Hypertension:
 • Hypertensive emergency
 • Hypertensive encephalopathy
- Differential Diagnosis ... Seizures/NCSE • Delirium ... renal crises Drug ... Sympathomimetic agents ... inhibitors Drug
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... 24-72 hours of drug ... to alternative agents ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
alcohol abuse or drugs ... Ataxia, Coma, Delirium ... Refeeding #Syndrome #diagnosis ... #pathophysiology
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
synthase à fungicidal agent ... vs Candida -> Drug ... But higher MICs ... Anidulafungin #Pharmacology