11 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... Pathophysiology #Pharmacology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
renal failure • Drugs ... uropathies • Drugs ... hyperplasia • Drugs ... nephropathy • Drugs ... #potassium #differential
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications ... #druginduced
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Renal failure (acute ... Drugs II. ... Drug-induced hyperkalemia ... Potassium-sparing ... anti-inflammatory drugs
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup - Differential ... deficiency • Drugs ... Hyperphosphatemia, Acute ... Hypocalcemia #Workup #Differential ... Diagnosis #Algorithm #nephrology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Erythematosus > 100 drugs ... associated with drug-induced ... SLE High risk ... #medications #drugs
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
starvation - Acute ... osmotic diuresis - Potassium ... renal disease Drugs ... #medications #drugs ... #pharmacology #
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... reactions Common Drugs ... • Recent IV potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... reactions Common Drugs ... • Recent IV potassium ... #high #nephrology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
after starvation, Acute ... osmotic diuresis, Potassium ... renal disease • Drugs ... Hypomagnesemia #Causes #differential ... #diagnosis #nephrology