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Medications associated with drug-induced lupus

List of Definite and Possible Associated Drugs

#Diagnosis #Pharmacology #Medications #DrugInduced #Lupus #List
associated with drug-induced ... Possible Associated Drugs ... #Diagnosis #Pharmacology ... #Differential # ... Drugs
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
renal failure • Drugs ... uropathies • Drugs ... hyperplasia • Drugs ... nephropathy • Drugs ... #potassium #differential
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Drugs II. ... Drug-induced hyperkalemia ... Potassium-sparing ... anti-inflammatory drugs ... #differential #
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications ... #druginduced
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Erythematosus > 100 drugs ... associated with drug-induced ... SLE High risk ... #medications #drugs
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • Clenching of fist ... reactions Common Drugs ... - Metabolic acidosis ... #high #nephrology
Numerous drugs taken by elderly persons can affect water balance by direct action on the kidney
Numerous drugs taken ... #Diagnosis #Pharmacology ... #Medications #DrugInduced ... #List #Differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • Clenching of fist ... reactions Common Drugs ... - Metabolic acidosis ... #high #nephrology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Acidosis B. ... Drugs: nonsteroidal ... anti-inflammatory drugs ... Drug-associated: ... #Diagnosis #High