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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Erythematosus #SLE ... #hematology #rheumatology ... #differential # ... diagnosis #causes
Drugs Commonly Implicated as Triggers of Drug Induced Thrombocytopenia
#Diagnosis #Hematology #Thrombocytopenia #Differential #DrugInduced #Medications
Drugs Commonly Implicated ... as Triggers of Drug ... Thrombocytopenia #Diagnosis ... #Hematology #Thrombocytopenia ... #Differential #
Lupus Classification
Spontaneous Lupus
 - Cutaneous Lupus Erythematosus (CLE)
 - Systemic Lupus Erythematosus 
Drug-Induced Lupus
 - Drug-Induced
Erythematosus Drug-Induced ... Lupus - Drug-Induced ... - Drug-Induced ... erythematosus #rheumatology ... #diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... disease (MCTD), Drug-induced ... erythematosus (SLE ... ANA #patterns #rheumatology ... #diagnosis #differential
Medications associated with drug-induced lupus

List of Definite and Possible Associated Drugs

#Diagnosis #Pharmacology #Medications #DrugInduced #Lupus #List
lupus List of ... #Diagnosis #Pharmacology ... #DrugInduced #Lupus ... #List #Causes #Differential ... #Drugs
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Pancytopenia - Differential ... Diagnosis Algorithm ... Radiation • Drugs ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Diagnosis Algorithm ... methotrexate) • Drugs ... Autoimmune • ITP • SLE ... anti-HLA antibodies Drugs ... #Causes #Hematology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Lupus Erythematosus ... SLE High risk ... #pharmacology # ... risk #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
involvement 3% SLE-Related ... Diagnosis and Lupus ... Mimickers: Drug-induced ... Lupusreference #SLE ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... cases, drug-dependent ... #table #rheumatology ... #diagnosis #management