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Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
, Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... Glomerulonephritis #MPGN
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... Henoch-SchonIein Purpura Anti-GBM ... to Kidney: Anti-GBM ... involvement: Anti-GBM
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Glomerulonephritis #RPGN
Kidney Biopsy - Diagnosis Algorithms 1) Normal Glomerulus by LM 2) Glomerular Crescents 3) Double Contours of GBM 4) Endocapillary
Double Contours of GBM ... Algorithm #nephrology #pathology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Atlas #Microscopy #Pathology ... Robbins & Cotran Pathologic
Guide to systemic mastocytosis Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
aggregates) in BM ... are atypical on BM ... Hypercellular BM ... criteria for MDS or MPN ... mastocytosis #hemepath #pathology
Stage III Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM from a biopsy with membranous
more extensive GBM ... surface of reticular GBM ... glomerulonephritis #MGN ... #stage3 #GBM #ElectronMicroscopy ... clinical #nephrology #pathology
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 Stage II Membranous Glomerulonephritis on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a glomerulus
appearance of GBM ... glomerulonephritis #MGN ... #stage2 #GBM #ElectronMicroscopy ... clinical #nephrology #pathology
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 Hypoxemia / Hypoxia - Rapid Response Management Algorithm Stridor - Upper airway pathology: • Anaphylaxis • Foreign
- Upper airway pathology ... - Lower airway pathology ... disorders (e.g., GBS
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