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diagnosis clinical nephrology blood differential bloodsmear glomerulonephritis microscopy path algorithm classification glomerular hematology pathology renal syndrome acanthocytes anemia blister blistercells
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
, Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Acanthocyte on Urine Microscopy Not a spaceship, not a UFO, just an acanthocyte caught “flying” in dark
Acanthocyte on Urine ... a UFO, just an acanthocyte ... presentation of RPGN ... VelezNephHepato #Acanthocyte
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 Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... Glomerulonephritis #MPGN
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... StanfordChiefs #RPGN
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... Glomerulonephritis #RPGN
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
Beautiful acanthocytes ... @MoravekMD #acanthocytes ... McLeod #Syndrome #Smear
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
also shows an acanthocyte ... BloodSmear #Blood #Smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... showed numerous acanthocytes ... Acanthocytes are ... peripheral #blood #smear
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
, a spur cell (acanthocyte ... BloodSmear #Blood #Smear
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Liver, kidney (MPGN
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