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visualabstract diagnosis nejm management nephrology differential pocus cardiology criticalcare ultrasound algorithm table comparison pathology causes im pulmonary trial clinical em
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
, Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... to Kidney: Anti-GBM ... involvement: Anti-GBM ... StanfordChiefs #RPGN
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Glomerulonephritis #RPGN
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... immune deposits on EM ... Glomerulonephritis #MPGN
Acanthocyte on Urine Microscopy Not a spaceship, not a UFO, just an acanthocyte caught “flying” in dark
presentation of RPGN
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 HUGS – Haloperidol for Gastroparesis #EBM #EM #GI #Haloperidol #Gastroparesis #FOAMCast
Gastroparesis #EBM ... #EM #GI #Haloperidol
Summary of Evidence for Mechanical CPR for OHCA #EBM #EM #Prehosp #MechanicalCPR #Mechanical #CPR #OHCA
CPR for OHCA #EBM ... #EM #Prehosp #MechanicalCPR
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Electron Microscopy (EM ... GN • Amyloid RPGN ... • Anti-GBM disease
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Liver, kidney (MPGN
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... atypical HUS; MPGN
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