12 results
diagnosis nephrology glomerulonephritis pathology clinical differential algorithm electronmicroscopy membranous sem classification glomerular hematology renal chronic cll comparison cryoglobulinemia disease diseases
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
, Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Mesangiocapillary GN ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... Glomerulonephritis #MPGN
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... Complement: Post-strep GN ... to Kidney: Anti-GBM ... StanfordChiefs #RPGN
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... post-infectious GN ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Glomerulonephritis #RPGN
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Liver, kidney (MPGN
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Post-infectious GN ... • Membranous GN ... • Amyloid RPGN ... • Anti-GBM disease ... pathology #comparison #table
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... basement membrane; GN ... atypical HUS; MPGN
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• MPGN: Paraneoplastic
Stage III Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM from a biopsy with membranous
more extensive GBM ... surface of reticular GBM ... glomerulonephritis #MGN ... #stage3 #GBM #ElectronMicroscopy
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 Guide to systemic mastocytosis Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
aggregates) in BM ... are atypical on BM ... release • MCs in BM ... Hypercellular BM ... criteria for MDS or MPN
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