23 results
nephrology clinical pathology electronmicroscopy glomerulus diagnosis glomerulonephritis differential gbm amyloid deposits desposition membranous mgn tuft algorithm classification hematology membranoproliferative microscopy
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
HTN, Vasculitis Glomerular ... , Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... formation along glomerular ... , CFHR5 neph) MPGN ... immune deposits on EM ... Glomerulonephritis #MPGN
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... with evidence of glomerular ... immune deposits in glomeruli ... staining on IF • No EM ... Glomerulonephritis #RPGN
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... StanfordChiefs #RPGN
Acanthocyte on Urine Microscopy Not a spaceship, not a UFO, just an acanthocyte caught “flying” in dark
presentation of RPGN
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 Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... atypical HUS; MPGN ... differential #diagnosis #glomerular
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... Electron Microscopy (EM ... GN • Amyloid RPGN ... polyangiitis #glomerular
This image shows acellular scanning EM with normal glomerular tuft at top and segmental necrosis at
acellular scanning EM ... with normal glomerular ... #necrosis #glomerular ... #tuft #glomerulus ... ElectronMicroscopy #SEM
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 Normal Glomerulus on Electron Microscopy This eyeSCANdy image shows scanning EM of normal glomerulus showing glomerular capillary
Normal Glomerulus ... shows scanning EM ... of normal glomerulus ... showing glomerular ... ElectronMicroscopy #SEM
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 Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Liver, kidney (MPGN
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