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clinical diagnosis smear pathology microbiology differential nephrology hematology algorithm bloodsmear peripheral culture glomerulonephritis path urine renal rheumatology causes comparison electronmicroscopy
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
, Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... Glomerulonephritis #MPGN
Acanthocyte on Urine Microscopy Not a spaceship, not a UFO, just an acanthocyte caught “flying” in dark
Acanthocyte on Urine Microscopy ... Urinary Sediment Microscopy ... presentation of RPGN ... Acanthocyte #Urine #Microscopy
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 Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... StanfordChiefs #RPGN
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... Glomerulonephritis #RPGN
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
diseases Light Microscopy ... Immunofluorescence Microscopy ... IM) - Electron Microscopy ... GN • Amyloid RPGN ... polyangiitis • Microscopic
Peripheral blood eosinophils, Phase contrast microscopy, time lapse, 100x |Olympus CH30| Carlos Martínez Figueroa @CarlosMartnezF7 #eosinophils #Peripheral #blood
Peripheral blood ... Phase contrast microscopy ... eosinophils #Peripheral #blood ... smear #clinical #microscopy
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 Peripheral blood neutrophil, phase contrast microscopy, time lapse, 100x. Olympus CH30 Carlos Martínez Figueroa @CarlosMartnezF7 #neutrophil #Peripheral #blood
Peripheral blood ... phase contrast microscopy ... neutrophil #Peripheral #blood ... smear #clinical #microscopy
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 Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Liver, kidney (MPGN
Babesia spp. on Peripheral Blood Smear Microscopy - Multiple small parasites per RBC - "maltese cross"
on Peripheral Blood ... Smear Microscopy ... Babesia #clinical #microscopy ... microbiology #peripheral #blood
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