35 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... • Differentiate ... #diagnosis #causes ... #hematology
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
- Differential ... • Deep Vein Thrombosis ... Marfan's Syndrome ... Vascular #JointPain #MSK ... #Orthopedics #Causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential ... • Nephrotic Syndrome ... antibodies (APLS should ... pathophysiology #hematology ... #differential #
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... Deconditioning - Pain ... #dyspnea #sob #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Drug induced - Bone ... Kasabach-Merritt syndrome ... #Diagnosis #hematology ... #rheumatology #
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework Bone ... /Joint Causes of ... #differential # ... lower #extremity #msk
Lemierre's Syndrome on Neck POCUS with IJ Thrombosis - Transverse View

Male with high fever and right
POCUS with IJ Thrombosis ... along with chest pain ... Differential/diagnosis ... case. ... On ultrasound note
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... Rule out other causes ... #Rheumatology # ... diagnosis #management #Dermatology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... folate def - Bone ... antiphospholipid syndrome ... Diagnosis #Framework #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... - Thrombotic ... #differential # ... diagnosis #hematology