19 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... paralysis of all extremity ... axonal form • MRI ... #Syndrome #diagnosis ... management #treatment #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Demyelinating Disease (MS ... Poliomyelitis, Guillain-Barre ... #diagnosis #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... paralysis of all extremity ... #Syndrome #diagnosis ... #management #neurology
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
Upper Extremity ... anesthesia and deltoid weakness ... Dermatomes #Myotomes #diagnosis ... #neurology #sensory ... #motor #arm #physicalexam
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Inflammatory/AI ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
- Emergency Causes ... cord • Guillain-Barre ... weakness and sensory ... Imaging studies: • MRI ... #causes #neurology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
• Cauda Equina Syndrome ... Commonly caused ... claudication and weakness ... #neurology #sensory ... #motor #leg #physicalexam
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
- Differential Diagnosis ... Herpes zoster - HIV ... #differential #diagnosis ... #lower #extremity ... #msk #physicalexam
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... pachymeningitis • HIV ... neuropathy (LHON) plus MRI ... consistent with MS ... #neurology #noninflammatory
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... , lower extremity ... #neurology #differential