17 results
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
... laboratory tests ... MRI, iADL scale, ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Frontal atrophy Vascular
Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic
Guillain–Barré syndrome ... syndrome:  Most ... common cause of ... acute flaccid paralysis ... Differential diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... injury, often from vascular ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... activity of factor X, vascular ... hypoadrenalism • Nausea ... enlargement • MRI
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... and sensitive tests ... the underlying pathophysiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
PCB variants of GBS ... /Edrophonium test ... - Cogan sign ... - Peek sign 2. ... aspiration and acute
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... Impairment: • Acute ... Inflammatory: Myeloma/amyloid ... Lack of UMN/LMN signs ... EMG) studies • MRI
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine • MCC- acute ... - Emergency Causes ... lumbar stenosis • Vascular ... Imaging studies: • MRI ... #causes #neurology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... anterior/posterior MSK ... : ACUTE, fever, ... #Management #Signs