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diagnosis management differential cardiology pharmacology treatment potassium causes ekg indications bloodpressure comparison evaluation hypertension inpatient nephrology neurology progression acei agents
Progressive ECG changes with increasing hyperkalaemia. (a) Normal (b) Tented T wave (arrow)
Progressive ECG ... changes with increasing ... hyperkalaemia ... d) 'Sine wave' pattern ... #ECG #Hyperkalemia
Compelling and Possible Contraindications to Antihypertensive Drugs Diuretics (thiazides) - Gout - Metabolic syndrome, Glucose intolerance, Pregnancy,
potential Ca2+ channel ... failure Ca2+ channel ... failure - Co-medication ... Pgp-dependent drugs (e.g ... contraindications #table
Constipation - Differential Diagnosis Algorithm Diet/Lifestyle • Fibre • Calories • Fluid • Exercise • Psychosocial Medications •
Differential Diagnosis Algorithm ... Psychosocial Medications ... Neurally Active Medications ... Hypothyroidism • Hypokalemia ... • Hypercalcemia
Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... , changes on ECG ... Figure 3 is an algorithm ... , and Table 3 summarizes ... medications used
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 Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia. - At
Hyperkalemia shortens ... repolarization; changes ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Algorithm • IV ... potassium and ECG ... changes • 5.5 ... morphology, "Sine wave" pattems
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
in kidneys) - Medications ... (e.g. lithium, ... cisplatin) - Chronic hypercalcemia ... - Chronic hypokalemia ... Differential #Diagnosis #Table
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Heparin) • Sodium-channel ... • Increased EC ... MunerMohamed1 #hyperkalemia ... pharmacology #potassium #medications
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... ECG changes, weakness ... injury, etc) ECG ... changes?
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... • Mechanism: Exchanges ... #medications #pharmacology ... #table #comparison
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