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diagnosis diabetes differential endocrinology management causes dm2 perioperative pharmacology preoperative risk stratification algorithm approaches associations bleeding cancers comparison dislocation em
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... Action: Inhibits DPP ... inactivates GLP-1 and GIP ... Januvia) - Once/day tablet ... Major Advantages
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
Medications Summary Table ... receptor agonists - ↓ major ... events TZDs DPP ... inhibitors - ↓ major ... #medications #table
Lymphadenopathy - Differential Diagnosis Algorithm Localized: • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
• Cervical: EBV ... , CMV, HIV, Toxo ... Infection: Acute HIV ... , EBV, Mycobacterial ... Anti-epileptic drugs (AEDs
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... - NEJM 2011 - Hip ... /vmoitra) #EBM
Selected Treatments for Hip Fracture. Panel A shows internal fixation with multiple screws for a nondisplaced
Treatments for Hip ... with a sliding hip ... recommended for stable ... hemiarthroplasty and a total hip ... Management #Ortho #EM
Interphalangeal Joint Dislocation Interphalangeal joint dislocations almost always occur dorsally, look for associated avulsion fractures! Here's a
• PIP joints are ... usually dorsal • DIP ... and PIP joints ... dislocation, due to EDS ... MH/CCF/CWRU EM
Infection-Related Cancers Viruses: • HPV - Cervical, anogenital, head and neck, skin cancer • HTLV-1 - Adult
T-cell Leukemia • HIV ... Kaposi's sarcoma • EBV ... differential #diagnosis #table
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
drug to remain stable ... morning, with just a sip ... patients to take meds ... empagliflozin and DPP4
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Evaluation Major ... functional status - Able ... metabolic equivalent able ... Stable patients ... Cataract Plan for Meds
Bleeding Risk for Various Invasive/Surgical Procedures Low Risk: • Dental extractions (1 or 2 teeth), endodontic (root
replacement) • Major ... anastomosis) • Major ... aortofemoral bypass) • Major ... surgery (e.g. hip ... Perioperative #Procedures #Table
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