461 results
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
receptor agonists - ↓ major ... inhibitors - ↓ major ... comparison #management #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Glyburide (Glynase) Major ... DM2 #diabetes #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
- Beware of major ... Diagnosis #Algorithm #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
Once/day tablet Major ... DM2 #diabetes #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Take with meals Major ... DM2 #diabetes #endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
Canagliflozin (Invokana) Major ... DM2 #diabetes #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
tablet (Rybelsus) Major ... DM2 #diabetes #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
birth • Labia major ... pathophysiology #genetics #endocrinology
Adrenal Insufficiency Treatment - Stress Dose Steroids
 • Large Bore IVs, ~2L IVF & Draw workup
-75mg daily • Major ... StressDose #Steroids #endocrinology
Major and Minor Criteria for Rheumatic Fever
#Diagnosis #RheumaticFever #Major #Minor #Jones #Criteria #CAFEPAL #Mnemonic
Major and Minor ... RheumaticFever #Major