34 results
diagnosis hematology rheumatology algorithm cutaneous leukemia monoclonal systemic causes chronic cll gammopathy generalized infections infectiousdiseases lymphocytic manifestations myelodysplastic pruritus secondary
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... #differential # ... diagnosis #dermatology ... #oncology #clinical ... #skin
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Cholestatic liver disease ... renal failure/uremia ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Systemic amyloidosis, Nodular ... Cold agglutinin disease ... , Syndrome Schnitzler ... manifestations #dermatology ... #skin #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... vasculitis #Dermatologic
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ulceration • Ocular ... (Clinical Dx). ... ) Differential Diagnosis ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... Headaches • Pale skin ... #oncology #hematology ... #diagnosis #management
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology ... #differential #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... (-) hemolytic anemia ... #Monoclonal #Differential ... #Diagnosis #Oncology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Arthralgia/arthritis, Skin ... fraction < 20% Differential ... • Ocular: uveitis ... #diagnosis #management
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome
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