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diagnosis differential antiarrhythmics cardiology fracture orthopedics pharmacology acutekidneyinjury aki complications dermatology disruptors eczematous hearing loss malunion nephrology nonunion otolaryngology otology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
out K+ efflux • Delays ... Vaughan Williams Classification ... ↑ QT interval (delays ... #Pharmacology #Classification ... #Classes #pathophysiology
Delayed Fracture Healing - Non-Union - Malunion - Differential Diagnosis Algorithm Inflammation (Hours-Days) -> Soft Callus (Days-Weeks)
Healing - Non-Union ... Excessive bone gap ... #Fracture #Healing ... NonUnion #Malunion #MSK ... #Orthopedics #Causes
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
AKI) What to ask ... - BMP, cap, CBC ... rhabdo/TLS) Causes ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... Action, ↑ EFR & AP ... ↑ QT interval (delays ... #Pharmacology #Classification ... #Classes #pathophysiology
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
(bilateral age related ... neuroma) and stroke may ... Head and neck masses ... (80% to 90% of cases ... Noise trauma ○ MS
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Differential Diagnosis Algorithm ... vesicles, erosions scaling ... May occur in anyone ... - Allergic - Delayed ... #causes
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
bone formation MSK ... Skull expansion causes ... middle ear bones causes ... -> Conductive hearing ... PagetsDisease #pathophysiology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Factors that may ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology
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