14 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
cytotoxic therapies in high-burden ... chemosensitive malignancy ... ) occur in high ... malignancies Treatments ... Lysis #Syndrome #TLS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... Diuretics, PRBC transfusion ... Spontaneous if high ... hydration - Hyperkalemia
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... Hyperaldosteronism: malignant ... Gitelman's syndrome #Hypokalemia ... #nephrology #causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Syndrome • HTN, High ... Aldosterone: Malignant ... #causes #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... wasting from other causes ... urinary losses: • High ... ↑ Aldosterone: Malignant ... #diagnosis #Algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... - Seizures - Malignant ... - Neuroleptic malignant ... HIV, Influenza, TSS ... Diagnosis #Management #causes
Treatment algorithm for malignancy-associated hypercalcemia.
Hypercalcemia
 - Renal Failure → Dialysis with low Ca++ bath
Aggressive IV hydration
Treatment algorithm ... for malignancy-associated ... Calcitonin Refractory Cases ... or Denosumab #malignancy ... #Treatment #algorithm
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Excessive insulation, high ... device • Blood transfusion ... • Neuroleptic malignant ... antipsychotics) • Malignant
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Acidosis, Cell Lysis (TLS ... ischemia, hemolysis, transfusions ... only if no clear cause ... Redistribution Treatments
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
training, Seizures, Malignant ... HIV, Influenza, TSS ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment