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diagnosis differential management treatment causes hivaids idsa prevention algorithm anemia aviumcomplex cd4 classification cmv cytomegalovirus erythematosus extravascular hemolysis hemophagocytic hlh
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... suppression (e.g. drugs ... Production #Index #hematology ... differential #diagnosis #calculation
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
delayed HTR • Drug-induced ... Hemolysis within circulation ... - Infections ... • PNH • Drug-induced ... Algorithm #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... →Activation of CD8 ... Still disease, Infection ... immune deficiency, Drugs ... treatment #summary #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
• Persistent CD4 ... deficiencies • CD4 ... ) • Drugs (corticosteroids ... myelodysplasia) • Infections ... ICL #diagnosis #hematology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Cytomegalovirus Infections ... ART to maintain CD4 ... intraocular levels of drug ... Treatment #management #opportunistic ... #pharmacology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... extremities Drug ... • Antihistone: Drug ... Erythematosus #Diagnosis #Rheumatology
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS Preventing 1st Episode of Disseminated
Prophylaxis: • CD4 ... necessary based on drug-drug ... Treatment #management #opportunistic ... #infections #HIVAIDS ... #pharmacology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis • Drug ... to exclude are infections ... Lab Tests: • CBC ... polyarteritis, drug-induced ... differential #diagnosis #rheumatology
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