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diagnosis causes algorithm management aplastic calculation erythematosus hodgkins index leukemia lupus lymphoma mcv mds mycobacteria myelodysplasia myelodysplastic nontuberculous ntm pancytopenia
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... malignancies • Infection ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... #Differential #
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... , G6PD deficiency ... Production #Index #hematology ... #anemia #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Inflammation, Chronic Infection ... #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Megaloblastic anemia-rare ... - Copper deficiency-rare ... #differential # ... diagnosis #causes #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Difficulty breathing • Neutropenia ... - recurrent infections ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
all phases of maturation ... - infiltrates (anemia ... or functional neutropenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease • Neutropenia ... • Parvovirus infection ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... Bone Marrow - Anemia ... , neutropenia ... #differential # ... diagnosis #infectiousdiseases
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... fibromyalgia) • Infections ... disease • Prolidase deficiency ... lymphopenia, low PLT • Anemia
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