14 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Diagnosis Algorithm ... malignancies • Infection ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
) - Differential ... Diagnosis Algorithm ... Inflammation, Chronic Infection ... #MCV #Classification ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Diagnosis Framework ... Macroangiopathic, Infections ... #Differential # ... Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Reticulocytes, MCV ... #Classification ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Difficulty breathing • Neutropenia ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... Diagnosis Neonate ... Megaloblastic anemia-rare ... - Copper deficiency-rare ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... necrosis) • VIT K deficiency ... #Diagnosis #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... translocation • Types: Classification ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
all phases of maturation ... - infiltrates (anemia ... or functional neutropenia ... #Leukemia #Hematology ... #Oncology #Diagnosis